Across TCGA patient cohorts, LY6G6C protein abundance is significantly associated with the RNA expression of many other genes, with 4,234 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LY6G6C-associated genes across cancer lineages are LGALSL, LYPD3, and DSG1. Each is linked with LY6G6C in more than 2 cancer types. Because this analysis shows association rather than direction, both LY6G6C-to-partner and partner-to-LY6G6C results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LY6G6C→partner) and Y-score (partner→LY6G6C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LGALSL →	+1.601	+2.701	.001	.001	3	3
LSCC	LYPD3 →	+1.548	+1.826	.004	.006	3	3
HNSC	DSG1 →	+3.374	+1.634	<.001	<.001	3	3
HNSC	SPRR2G →	+2.930	+0.970	<.001	<.001	3	3
LSCC	PGLYRP3 →	+3.124	+2.443	<.001	.003	3	3
LSCC	TGM6 →	+2.080	+2.650	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,234 associations by consensus.

Exploration

LY6G6C survival (RNA) · tumor vs normal (RNA) · all LY6G6C data types