Across TCGA patient cohorts, LY6G6C mutation is significantly associated with the RNA expression of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LY6G6C-associated genes across cancer lineages are RN7SL769P, OR1AC1P, and RNA5SP426. Each is linked with LY6G6C in more than 1 cancer types. Because this analysis shows association rather than direction, both LY6G6C-to-partner and partner-to-LY6G6C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LY6G6C→partner) and Y-score (partner→LY6G6C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL769P →	+0.530	+3.847	.001	.008	3	2
UCEC	OR1AC1P →	+0.555	+4.352	<.001	.008	3	2
UCEC	RNA5SP426 →	+0.417	+4.868	<.001	.004	3	2
UCEC	MIR6842 →	+0.640	+5.137	<.001	.003	3	1
UCEC	SNORD116-22 →	+0.395	+4.267	.004	.009	3	1
SKCM	MIR6074 →	+0.543	+7.219	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

Exploration

LY6G6C survival (RNA) · tumor vs normal (RNA) · all LY6G6C data types