LY6G5C

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LY6G5C mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LY6G5C-associated genes across cancer lineages are LINC02333, IGKV2OR2-10, and FAM170B. Each is linked with LY6G5C in more than 1 cancer types. Because this analysis shows association rather than direction, both LY6G5C-to-partner and partner-to-LY6G5C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LY6G5C→partner) and Y-score (partner→LY6G5C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECLINC02333 →+0.093+4.567.002.00131
UCECIGKV2OR2-10 →+0.168+5.522<.001<.00131
UCECFAM170B →+0.284+3.847<.001.00831
COADRNU6-1210P →+0.553+7.741<.001.00931
COADFAM41AY1 →+0.074+7.741<.001.00931
COADYRDCP3 →+0.161+7.741<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

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