LY6D

Across TCGA patient cohorts, LY6D protein abundance is significantly associated with the RNA expression of many other genes, with 8,376 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LY6D-associated genes across cancer lineages are KRT16, TRIM29, and ZNF185. Each is linked with LY6D in more than 5 cancer types. Because this analysis shows association rather than direction, both LY6D-to-partner and partner-to-LY6D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LY6D versus KRT16 in UCEC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LY6D→partner) and Y-score (partner→LY6D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KRT16 →	+3.082	+1.309	<.001	.001	3	6
BRCA	TRIM29 →	+1.825	+1.625	<.001	<.001	3	5
UCEC	ZNF185 →	+1.109	+1.617	<.001	<.001	3	5
UCEC	GSDMC →	+1.367	+1.787	<.001	<.001	3	5
PDAC	ANXA8 →	+1.328	+1.340	<.001	<.001	3	5
HNSC	SLURP1 →	+2.095	+0.924	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,376 associations by consensus.

LY6D vs KRT16 — UCEC

Explore this scatter interactively →