Across TCGA patient cohorts, LUZP2 mutation is significantly associated with the RNA expression of many other genes, with 3,278 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LUZP2-associated genes across cancer lineages are E2F4, GMDS, and LARP1B. Each is linked with LUZP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both LUZP2-to-partner and partner-to-LUZP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LUZP2→partner) and Y-score (partner→LUZP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	E2F4 →	+0.376	+2.082	<.001	<.001	3	3
UCEC	GMDS →	+0.600	+2.010	<.001	.001	3	3
UCEC	LARP1B →	+0.458	+1.860	<.001	<.001	3	3
UCEC	TIPIN →	+0.515	+1.828	<.001	<.001	3	3
LUAD	PPP2R2D →	+0.329	+3.205	.002	.009	3	3
UCEC	POLE2 →	+0.463	+2.191	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,278 associations by consensus.

Exploration

LUZP2 survival (RNA) · tumor vs normal (RNA) · all LUZP2 data types