Across TCGA cell cohorts, LUZP2 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible LUZP2-associated genes across cancer lineages are OR1E2, COX6A2, and OR4X2. Each is linked with LUZP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LUZP2-to-partner and partner-to-LUZP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LUZP2→partner) and Y-score (partner→LUZP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR1E2 →	+0.013	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	COX6A2 →	+0.607	+3.977	.003	.005	3	1
LUNG_NSCLC_LUAD	OR4X2 →	+0.018	+3.947	<.001	.004	3	1
LUNG_NSCLC_LUAD	P2RY13 →	+0.019	+4.312	<.001	.005	3	1
LUNG_NSCLC_LUAD	SPDYE4 →	+0.030	+3.544	.008	.009	3	1
LUNG_NSCLC_LUAD	DCDC2C →	+0.075	+3.760	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

LUZP2 survival (RNA) · tumor vs normal (RNA) · all LUZP2 data types