LUC7L2

Across TCGA patient cohorts, LUC7L2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,146 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LUC7L2-associated genes across cancer lineages are XPO1, NCAPD2, and DNAJC2. Each is linked with LUC7L2 in more than 5 cancer types. Because this analysis shows association rather than direction, both LUC7L2-to-partner and partner-to-LUC7L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LUC7L2 versus XPO1 in HNSC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LUC7L2→partner) and Y-score (partner→LUC7L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	XPO1 →	+0.580	+0.415	<.001	<.001	3	5
HNSC	NCAPD2 →	+0.867	+0.318	.001	<.001	3	5
LSCC	DNAJC2 →	+0.479	+0.224	<.001	<.001	3	5
OV	RBM28 →	+0.554	+0.289	.004	.009	2	6
HNSC	EZH2 →	+0.846	+0.333	<.001	<.001	3	5
LSCC	SMC4 →	+0.869	+0.320	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,146 associations by consensus.

LUC7L2 vs XPO1 — HNSC

Explore this scatter interactively →