LUC7L2

Across TCGA patient cohorts, LUC7L2 mutation is significantly associated with the RNA expression of many other genes, with 1,699 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LUC7L2-associated genes across cancer lineages are MTHFD2P3, ACTL9, and MIR107. Each is linked with LUC7L2 in more than 2 cancer types. Because this analysis shows association rather than direction, both LUC7L2-to-partner and partner-to-LUC7L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTHFD2P3 grouped by LUC7L2-low versus LUC7L2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LUC7L2→partner) and Y-score (partner→LUC7L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MTHFD2P3 →	+0.120	+4.859	<.001	.004	3	3
HNSC	ACTL9 →	+0.163	+4.565	<.001	.004	3	2
HNSC	MIR107 →	+0.470	+4.578	<.001	.008	3	2
HNSC	RNA5SP405 →	+0.275	+5.608	<.001	.002	3	2
HNSC	RNA5SP161 →	+0.413	+4.505	<.001	.009	3	2
HNSC	RNU6-933P →	+0.691	+4.245	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,699 associations by consensus.

MTHFD2P3 by LUC7L2 expression — BLCA

Explore this box plot interactively →