LUC7L

Across TCGA patient cohorts, LUC7L mutation is significantly associated with the RNA expression of many other genes, with 2,729 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LUC7L-associated genes across cancer lineages are RN7SL248P, RN7SL478P, and HNRNPCP9. Each is linked with LUC7L in more than 1 cancer types. Because this analysis shows association rather than direction, both LUC7L-to-partner and partner-to-LUC7L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by LUC7L-low versus LUC7L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LUC7L→partner) and Y-score (partner→LUC7L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.058	+3.022	<.001	.001	3	2
BLCA	RN7SL478P →	+0.323	+4.268	<.001	.008	3	2
COAD	HNRNPCP9 →	+0.169	+3.646	<.001	.009	3	2
COAD	UBFD1P1 →	+0.110	+5.136	<.001	.002	3	2
COAD	RNU6-781P →	+0.271	+4.537	<.001	.006	3	2
BLCA	RN7SKP295 →	+0.258	+4.899	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,729 associations by consensus.

RN7SL248P by LUC7L expression — UCEC

Explore this box plot interactively →