LTBP1

Across TCGA patient cohorts, LTBP1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,040 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LTBP1-associated genes across cancer lineages are MYL9, NALCN, and CNN1. Each is linked with LTBP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both LTBP1-to-partner and partner-to-LTBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LTBP1 versus MYL9 in BRCA, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LTBP1→partner) and Y-score (partner→LTBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MYL9 →	+1.376	+0.663	<.001	<.001	3	7
PDAC	NALCN →	+0.630	+0.354	<.001	<.001	3	7
COAD	CNN1 →	+1.375	+0.487	.002	.003	3	7
BRCA	TAGLN →	+1.292	+0.693	<.001	<.001	3	7
CCRCC	FSTL1 →	+1.151	+0.782	<.001	<.001	3	7
CCRCC	IGFBP7 →	+0.826	+0.818	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,040 associations by consensus.

LTBP1 vs MYL9 — BRCA

Explore this scatter interactively →