Across TCGA patient cohorts, LTB4R2 protein abundance is significantly associated with the RNA expression of many other genes, with 97 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LTB4R2-associated genes across cancer lineages are AKT2, SNX4, and POLE4. Each is linked with LTB4R2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LTB4R2-to-partner and partner-to-LTB4R2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LTB4R2→partner) and Y-score (partner→LTB4R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AKT2 →	-1.245	-1.509	<.001	.005	3	1
BRCA	SNX4 →	-0.627	-1.538	.009	.002	3	1
BRCA	POLE4 →	+1.276	+1.769	.009	.005	3	1
BRCA	ERGIC3 →	+0.501	+1.270	.005	.002	3	1
BRCA	MLLT1 →	-0.902	-1.232	.002	.003	3	1
BRCA	SEMA4F →	+1.004	+1.927	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 97 associations by consensus.

Exploration

LTB4R2 survival (RNA) · tumor vs normal (RNA) · all LTB4R2 data types