LTB4R2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LTB4R2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LTB4R2-associated genes across cancer lineages are Memory B-cells, CD4+ memory T-cells, and MSC. Each is linked with LTB4R2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LTB4R2-to-partner and partner-to-LTB4R2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LTB4R2→partner) and Y-score (partner→LTB4R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMemory B-cells →+0.032+2.374.038.03931
UCECCD4+ memory T-cells →+0.023+1.939.028.04431
UCECMSC →-0.352-3.000.003.03711
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration