Across TCGA cell cohorts, LTB4R2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,471 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LTB4R2-associated GO terms across cancer lineages are Leukotriene signaling pathway, Negative regulation of DNA-templated transcription, elongation, and Regulation of nucleocytoplasmic transport. Each is linked with LTB4R2 in more than 17 cancer types. Because this analysis shows association rather than direction, both LTB4R2-to-partner and partner-to-LTB4R2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LTB4R2→partner) and Y-score (partner→LTB4R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Leukotriene signaling pathway →	+1.540	+1.822	<.001	<.001	3	18
OESOPHAGUS	Negative regulation of DNA-templated transcription, elongation →	+0.145	+2.467	<.001	<.001	3	17
PANCREAS	Regulation of nucleocytoplasmic transport →	+0.089	+1.240	<.001	<.001	3	17
OESOPHAGUS	Regulation of mRNA processing →	+0.094	+2.135	<.001	<.001	3	17
OESOPHAGUS	mRNA splice site recognition →	+0.200	+3.068	<.001	<.001	3	17
BONE	Pre-mRNA catabolic process →	+0.190	+1.048	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,471 associations by consensus.

Exploration

LTB4R2 survival (RNA) · tumor vs normal (RNA) · all LTB4R2 data types