Across TCGA cell cohorts, LTB4R2 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LTB4R2-associated genes across cancer lineages are C20orf173, TRIM42, and KRT84. Each is linked with LTB4R2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LTB4R2-to-partner and partner-to-LTB4R2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LTB4R2→partner) and Y-score (partner→LTB4R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	C20orf173 →	+0.025	+4.930	<.001	.008	3	1
SOFT_TISSUE	TRIM42 →	+0.023	+5.369	<.001	.004	3	1
SOFT_TISSUE	KRT84 →	+0.136	+4.930	<.001	.008	3	1
SOFT_TISSUE	KRT26 →	+0.015	+4.930	.006	.008	3	1
SOFT_TISSUE	KRTAP2-4 →	+0.070	+4.930	.004	.008	3	1
SOFT_TISSUE	KRTAP10-10 →	+0.023	+5.977	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

LTB4R2 survival (RNA) · tumor vs normal (RNA) · all LTB4R2 data types