LSR

Across TCGA patient cohorts, LSR RNA expression is significantly associated with the go_rna of many other GO terms, with 7,158 significant associations in total. KIRP shows the largest number of these associations.

The most reproducible LSR-associated GO terms across cancer lineages are Hematopoietic stem cell migration, Cell differentiation involved in embryonic placenta development, and Cardiac muscle cell-cardiac muscle cell adhesion. Each is linked with LSR in more than 16 cancer types. Because this analysis shows association rather than direction, both LSR-to-partner and partner-to-LSR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hematopoietic stem cell migration grouped by LSR-low versus LSR-high in READ.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LSR→partner) and Y-score (partner→LSR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	Hematopoietic stem cell migration →	-0.047	-0.622	<.001	<.001	3	17
UCS	Cell differentiation involved in embryonic placenta development →	+0.056	+1.715	<.001	<.001	3	15
UCS	Cardiac muscle cell-cardiac muscle cell adhesion →	+0.127	+2.261	<.001	<.001	3	15
THYM	Tight junction organization →	+0.060	+1.374	<.001	<.001	3	15
PAAD	ERBB3 signaling pathway →	+0.107	+1.013	<.001	<.001	3	15
ESCA	Sphingomyelin catabolic process →	+0.087	+0.611	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,158 associations by consensus.

Hematopoietic stem cell migration by LSR expression — READ

Explore this box plot interactively →