LSP1

Across TCGA cell cohorts, LSP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,545 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LSP1-associated GO terms across cancer lineages are Regulation of telomere maintenance, Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration, and Positive regulation of chromosome organization. Each is linked with LSP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both LSP1-to-partner and partner-to-LSP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomere maintenance grouped by LSP1-low versus LSP1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LSP1→partner) and Y-score (partner→LSP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of telomere maintenance →	+0.075	+1.132	<.001	<.001	3	8
OESOPHAGUS	Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration →	+0.146	+1.065	<.001	.004	3	7
PANCREAS	Positive regulation of chromosome organization →	+0.054	+1.025	<.001	<.001	3	7
BREAST	Regulation of protein localization to mitochondrion →	+0.095	+0.662	.005	.003	3	7
OESOPHAGUS	Positive regulation of telomere maintenance →	+0.081	+0.695	<.001	.001	2	8
OESOPHAGUS	Caveolin-mediated endocytosis →	+0.177	+1.384	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,545 associations by consensus.

Regulation of telomere maintenance by LSP1 expression — OESOPHAGUS

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