LSMEM2

Across TCGA patient cohorts, LSMEM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,619 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LSMEM2-associated proteins across cancer lineages are COPB1, PHRF1_S814, and RPL5. Each is linked with LSMEM2 in more than 4 cancer types. Because this analysis shows association rather than direction, both LSMEM2-to-partner and partner-to-LSMEM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LSMEM2 versus COPB1 in LSCC, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LSMEM2→partner) and Y-score (partner→LSMEM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	COPB1 →	-0.173	-0.304	<.001	<.001	3	5
CCRCC	PHRF1_S814 →	-0.437	-0.278	<.001	<.001	3	4
GBM	RPL5 →	-0.192	-0.404	<.001	<.001	3	4
HNSC	CASP4 →	-0.397	-0.301	.003	.003	3	4
LSCC	POLR2A →	+0.139	+0.250	<.001	<.001	3	3
COAD	SEC23B →	-0.241	-0.121	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,619 associations by consensus.

LSMEM2 vs COPB1 — LSCC

Explore this scatter interactively →