LSMEM1

Across TCGA cell cohorts, LSMEM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,569 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LSMEM1-associated GO terms across cancer lineages are Taurine biosynthetic process, Negative regulation of translational initiation, and Alkanesulfonate biosynthetic process. Each is linked with LSMEM1 in more than 9 cancer types. Because this analysis shows association rather than direction, both LSMEM1-to-partner and partner-to-LSMEM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Taurine biosynthetic process grouped by LSMEM1-low versus LSMEM1-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LSMEM1→partner) and Y-score (partner→LSMEM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Taurine biosynthetic process →	+0.778	+0.708	<.001	<.001	3	10
BREAST	Negative regulation of translational initiation →	+0.083	+0.504	<.001	.003	3	10
CNS	Alkanesulfonate biosynthetic process →	+0.778	+0.708	<.001	<.001	3	10
PANCREAS	Pre-mRNA catabolic process →	+0.109	+0.747	<.001	<.001	3	10
OVARY	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.103	+0.790	<.001	<.001	3	10
CNS	Protein localization to lysosome →	+0.050	+0.622	.007	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,569 associations by consensus.

Taurine biosynthetic process by LSMEM1 expression — CNS

Explore this box plot interactively →