LSM5

Across TCGA patient cohorts, LSM5 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,351 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LSM5-associated proteins across cancer lineages are POLD2, MCM2, and MCM4. Each is linked with LSM5 in more than 8 cancer types. Because this analysis shows association rather than direction, both LSM5-to-partner and partner-to-LSM5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LSM5 versus POLD2 in BRCA, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LSM5→partner) and Y-score (partner→LSM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	POLD2 →	+0.403	+0.459	<.001	<.001	3	9
BRCA	MCM2 →	+0.627	+0.376	<.001	.001	3	8
LUAD	MCM4 →	+0.666	+0.489	<.001	<.001	3	8
BRCA	MCM7 →	+0.656	+0.390	<.001	.001	3	8
LSCC	PCNA →	+0.679	+0.632	<.001	<.001	3	8
BRCA	POLD1 →	+0.413	+0.479	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,351 associations by consensus.

LSM5 vs POLD2 — BRCA

Explore this scatter interactively →