LSM4

Across TCGA patient cohorts, LSM4 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LSM4-associated genes across cancer lineages are p27_pT157 and Rab11. Each is linked with LSM4 in more than 1 cancer types. Because this analysis shows association rather than direction, both LSM4-to-partner and partner-to-LSM4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p27_pT157 grouped by LSM4-low versus LSM4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LSM4→partner) and Y-score (partner→LSM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p27_pT157 →	-0.061	-2.960	.043	.036	3	1
UCEC	Rab11 →	-0.164	-2.980	.031	.036	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

p27_pT157 by LSM4 expression — UCEC

Explore this box plot interactively →