Across TCGA patient cohorts, LSM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,460 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LSM2-associated proteins across cancer lineages are MCM3, MCM4, and MCM5. Each is linked with LSM2 in more than 8 cancer types. Because this analysis shows association rather than direction, both LSM2-to-partner and partner-to-LSM2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LSM2→partner) and Y-score (partner→LSM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MCM3 →	+0.615	+0.918	<.001	<.001	3	9
OV	MCM4 →	+0.820	+0.496	<.001	.003	3	9
OV	MCM5 →	+0.709	+0.590	<.001	.002	3	9
OV	MCM7 →	+0.789	+0.561	<.001	.001	3	9
OV	PRIM2 →	+0.588	+0.604	<.001	.002	3	8
LSCC	RFC2 →	+0.391	+0.560	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,460 associations by consensus.

Exploration

LSM2 survival (RNA) · tumor vs normal (RNA) · all LSM2 data types