LSM12

Across TCGA cell cohorts, LSM12 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,577 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LSM12-associated GO terms across cancer lineages are DNA replication initiation, DNA replication, and DNA-templated transcription initiation. Each is linked with LSM12 in more than 12 cancer types. Because this analysis shows association rather than direction, both LSM12-to-partner and partner-to-LSM12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by LSM12-low versus LSM12-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LSM12→partner) and Y-score (partner→LSM12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	DNA replication initiation →	+0.167	+0.690	<.001	<.001	3	13
PANCREAS	DNA replication →	+0.095	+0.797	<.001	<.001	3	12
PANCREAS	DNA-templated transcription initiation →	+0.062	+0.710	<.001	<.001	3	12
BONE	Mitotic sister chromatid cohesion →	+0.132	+0.620	<.001	.004	3	12
BLOOD_Myeloma	Mitotic spindle organization →	+0.096	+0.626	.001	<.001	3	12
PANCREAS	Positive regulation of nuclear cell cycle DNA replication →	+0.120	+0.481	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,577 associations by consensus.

DNA replication initiation by LSM12 expression — BLOOD_Myeloma

Explore this box plot interactively →