LSM10

Across TCGA patient cohorts, LSM10 protein abundance is significantly associated with the RNA expression of many other genes, with 1,259 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LSM10-associated genes across cancer lineages are HSD11B1-AS1, RBMX2, and OR2A14. Each is linked with LSM10 in more than 1 cancer types. Because this analysis shows association rather than direction, both LSM10-to-partner and partner-to-LSM10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LSM10 versus HSD11B1-AS1 in BRCA, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LSM10→partner) and Y-score (partner→LSM10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HSD11B1-AS1 →	+0.790	+0.424	.005	.004	3	2
GBM	RBMX2 →	+0.568	+0.583	<.001	<.001	3	2
LUAD	OR2A14 →	+0.678	+0.550	<.001	<.001	3	2
GBM	CCT6P1 →	+0.754	+0.346	.008	.003	3	2
GBM	RNU6-1223P →	+1.988	+0.406	.001	.001	3	2
UCEC	RNASET2 →	+1.090	+2.366	.006	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,259 associations by consensus.

LSM10 vs HSD11B1-AS1 — BRCA

Explore this scatter interactively →