LSM10

Across TCGA cell cohorts, LSM10 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,555 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible LSM10-associated GO terms across cancer lineages are Protein-RNA covalent cross-linking repair, 7-methylguanosine cap hypermethylation, and Maintenance of blood-brain barrier. Each is linked with LSM10 in more than 11 cancer types. Because this analysis shows association rather than direction, both LSM10-to-partner and partner-to-LSM10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-RNA covalent cross-linking repair grouped by LSM10-low versus LSM10-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LSM10→partner) and Y-score (partner→LSM10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Protein-RNA covalent cross-linking repair →	+0.095	+0.549	.001	.001	3	12
SKIN	7-methylguanosine cap hypermethylation →	+0.086	+0.579	<.001	<.001	3	12
URINARY_TRACT	Maintenance of blood-brain barrier →	-0.221	-1.111	<.001	<.001	3	11
BREAST	Response to indole-3-methanol →	-0.229	-0.781	<.001	<.001	3	10
BREAST	Cellular response to indole-3-methanol →	-0.209	-0.943	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Cell junction assembly →	-0.083	-0.894	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,555 associations by consensus.

Protein-RNA covalent cross-linking repair by LSM10 expression — LIVER

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