LSG1

Across TCGA patient cohorts, LSG1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,650 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LSG1-associated genes across cancer lineages are NCBP2, WDR53, and EEF1AKMT4. Each is linked with LSG1 in more than 7 cancer types. Because this analysis shows association rather than direction, both LSG1-to-partner and partner-to-LSG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LSG1 versus NCBP2 in LSCC, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LSG1→partner) and Y-score (partner→LSG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NCBP2 →	+0.853	+0.549	<.001	<.001	3	8
LSCC	WDR53 →	+0.818	+0.579	<.001	<.001	3	8
LSCC	EEF1AKMT4 →	+1.228	+0.574	<.001	<.001	3	8
LSCC	MRPL47 →	+0.947	+0.538	<.001	<.001	3	7
LSCC	RFC4 →	+1.122	+0.565	<.001	<.001	3	7
OV	DNAJB11 →	+0.731	+0.395	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,650 associations by consensus.

LSG1 vs NCBP2 — LSCC

Explore this scatter interactively →