Across TCGA patient cohorts, LSAMP RNA expression is significantly associated with the protein abundance of many other proteins, with 18,415 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible LSAMP-associated proteins across cancer lineages are DPYSL2, PPM1F, and TMEM119. Each is linked with LSAMP in more than 6 cancer types. Because this analysis shows association rather than direction, both LSAMP-to-partner and partner-to-LSAMP results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LSAMP→partner) and Y-score (partner→LSAMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DPYSL2 →	+0.514	+0.839	.004	.001	3	7
PDAC	PPM1F →	+0.297	+0.649	<.001	<.001	3	7
OV	TMEM119 →	+0.787	+0.925	<.001	<.001	3	6
BRCA	PRKCA →	+0.541	+0.896	<.001	<.001	3	6
GBM	TMOD2 →	+0.555	+0.859	<.001	<.001	3	6
OV	ZCCHC24 →	+1.057	+1.521	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,415 associations by consensus.

Exploration

LSAMP survival (RNA) · tumor vs normal (RNA) · all LSAMP data types