LSAMP-AS1

Across TCGA pan-cancer cohorts, LSAMP-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated LSAMP-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LSAMP-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LSAMP-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUSC and ESCA show a favorable association.

KIRC, KICH, and CESC are the cancer types where LSAMP-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.433	0.670	<.001	102	view →
KICH	DFS	Tertile	III,IV	0.159	0.866	<.001	68	view →
CESC	DFS	Quartile	IV	0.152	0.599	<.001	68	view →
LUSC	DFS	Tertile	All	0.719	0.531	<.001	43	view →
LUAD	DFS	Tertile	IV	0.464	0.884	.008	28	view →
DLBC	OS	Tertile	IV	0.147	0.850	.002	27	view →
SARC	DFS	Median	All	0.519	0.701	<.001	27	view →
BLCA	DFS	Quartile	II,III,IV	0.517	0.683	.001	24	view →
UCEC	OS	Quartile	All	0.807	0.893	.004	20	view →
LAML	DFS	Tertile	All	0.138	0.426	.049	18	view →
LIHC	DFS	Tertile	All	0.329	0.459	.012	18	view →
THCA	DFS	Quartile	All	0.850	0.932	.015	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

LSAMP-AS1–KIRC (OS)

Open the KIRC breakdown →