LRWD1

Across TCGA patient cohorts, LRWD1 mutation is significantly associated with the RNA expression of many other genes, with 2,983 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LRWD1-associated genes across cancer lineages are NPLP1, LINC01072, and TRAJ34. Each is linked with LRWD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both LRWD1-to-partner and partner-to-LRWD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NPLP1 grouped by LRWD1-low versus LRWD1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRWD1→partner) and Y-score (partner→LRWD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	NPLP1 →	+0.112	+3.343	.001	.007	3	3
READ	LINC01072 →	+0.187	+5.421	<.001	.005	3	2
COAD	TRAJ34 →	+0.813	+2.830	<.001	.009	3	2
COAD	RNU6-918P →	+0.282	+4.655	<.001	<.001	3	2
COAD	LINC01682 →	+0.095	+5.149	<.001	.001	3	2
COAD	CENPNP2 →	+0.200	+3.343	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,983 associations by consensus.

NPLP1 by LRWD1 expression — COAD

Explore this box plot interactively →