LRRTM4

Across TCGA patient cohorts, LRRTM4 protein abundance is significantly associated with the RNA expression of many other genes, with 4,138 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRRTM4-associated genes across cancer lineages are UPB1, SNRPD3, and GRK3. Each is linked with LRRTM4 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRTM4-to-partner and partner-to-LRRTM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRTM4 versus UPB1 in GBM, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRTM4→partner) and Y-score (partner→LRRTM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	UPB1 →	+0.239	+0.537	<.001	<.001	3	1
GBM	SNRPD3 →	+0.469	+0.551	.001	.001	3	1
GBM	GRK3 →	+0.620	+0.480	<.001	<.001	3	1
GBM	SEZ6L →	+1.546	+0.575	.007	<.001	3	1
GBM	SOX10 →	+1.857	+0.521	<.001	.002	3	1
GBM	SEPTIN3 →	+0.860	+0.534	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,138 associations by consensus.

LRRTM4 vs UPB1 — GBM

Explore this scatter interactively →