LRRTM2

Across TCGA cell cohorts, LRRTM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,529 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible LRRTM2-associated GO terms across cancer lineages are Regulation of microtubule cytoskeleton organization, Regulation of cilium assembly, and Retrograde transport, endosome to Golgi. Each is linked with LRRTM2 in more than 8 cancer types. Because this analysis shows association rather than direction, both LRRTM2-to-partner and partner-to-LRRTM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of microtubule cytoskeleton organization grouped by LRRTM2-low versus LRRTM2-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRTM2→partner) and Y-score (partner→LRRTM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Regulation of microtubule cytoskeleton organization →	+0.041	+0.486	<.001	<.001	3	9
CNS	Regulation of cilium assembly →	+0.038	+0.523	.001	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Retrograde transport, endosome to Golgi →	+0.064	+0.127	.001	.004	3	8
KIDNEY	Negative regulation of telomere maintenance via telomere lengthening →	+0.044	+0.334	<.001	.001	3	7
LARGE_INTESTINE	DNA biosynthetic process →	+0.057	+0.066	<.001	.001	2	8
SKIN	Regulation of microtubule-based process →	+0.030	+0.673	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,529 associations by consensus.

Regulation of microtubule cytoskeleton organization by LRRTM2 expression — CNS

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