LRRTM1

Across TCGA patient cohorts, LRRTM1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,830 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRRTM1-associated genes across cancer lineages are PROX1-AS1, SLC8A3, and SNPH. Each is linked with LRRTM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRTM1-to-partner and partner-to-LRRTM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRTM1 versus PROX1-AS1 in UCEC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRTM1→partner) and Y-score (partner→LRRTM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PROX1-AS1 →	+1.548	+1.019	.001	.002	3	2
GBM	SLC8A3 →	+1.209	+0.390	.001	.009	3	2
UCEC	SNPH →	+1.268	+0.717	<.001	.001	3	2
GBM	PAK5 →	+1.148	+0.459	<.001	<.001	3	2
UCEC	FGF9 →	+2.169	+0.952	.006	.004	3	2
GBM	SEPTIN4 →	+0.960	+0.427	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,830 associations by consensus.

LRRTM1 vs PROX1-AS1 — UCEC

Explore this scatter interactively →