LRRTM1

Across TCGA cell cohorts, LRRTM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 435 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible LRRTM1-associated GO terms across cancer lineages are Cardiac muscle cell action potential, Spliceosomal complex assembly, and Negative regulation of adaptive immune response. Each is linked with LRRTM1 in more than 4 cancer types. Because this analysis shows association rather than direction, both LRRTM1-to-partner and partner-to-LRRTM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cardiac muscle cell action potential grouped by LRRTM1-low versus LRRTM1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRTM1→partner) and Y-score (partner→LRRTM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Cardiac muscle cell action potential →	-0.092	-0.027	.006	.006	2	5
LUNG_SCLC	Spliceosomal complex assembly →	+0.079	+1.148	.001	.005	3	4
LUNG_SCLC	Negative regulation of adaptive immune response →	-0.057	-1.041	.002	.008	3	4
LUNG_SCLC	Establishment of RNA localization →	+0.071	+0.818	<.001	.004	3	4
LUNG_SCLC	RNA localization →	+0.083	+1.335	.001	.002	3	4
LARGE_INTESTINE	Regulation of response to endoplasmic reticulum stress →	+0.042	+0.583	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 435 associations by consensus.

Cardiac muscle cell action potential by LRRTM1 expression — BREAST

Explore this box plot interactively →