LRRN4CL

Across TCGA cell cohorts, LRRN4CL RNA expression is significantly associated with the go_rna of many other GO terms, with 1,979 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LRRN4CL-associated GO terms across cancer lineages are L-kynurenine catabolic process, Kynurenine metabolic process, and ERAD pathway. Each is linked with LRRN4CL in more than 5 cancer types. Because this analysis shows association rather than direction, both LRRN4CL-to-partner and partner-to-LRRN4CL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-kynurenine catabolic process grouped by LRRN4CL-low versus LRRN4CL-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRN4CL→partner) and Y-score (partner→LRRN4CL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	L-kynurenine catabolic process →	-0.748	-1.652	.001	.001	3	6
SOFT_TISSUE	Kynurenine metabolic process →	-0.574	-1.442	.001	<.001	3	6
SOFT_TISSUE	ERAD pathway →	+0.064	+1.085	<.001	.009	3	5
BLOOD_Lymphoma	Nucleic acid catabolic process →	+0.025	+0.055	.004	.002	3	5
BLOOD_Lymphoma	Subtelomeric heterochromatin formation →	+0.084	+0.091	.001	.001	3	5
CNS	Multivesicular body sorting pathway →	+0.054	+1.056	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,979 associations by consensus.

L-kynurenine catabolic process by LRRN4CL expression — SOFT_TISSUE

Explore this box plot interactively →