LRRN4CL

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LRRN4CL mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRRN4CL-associated genes across cancer lineages are GSG1L2. Each is linked with LRRN4CL in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRN4CL-to-partner and partner-to-LRRN4CL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSG1L2 grouped by LRRN4CL-low versus LRRN4CL-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRN4CL→partner) and Y-score (partner→LRRN4CL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaGSG1L2 →+0.043+4.969<.001.00331
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

GSG1L2 by LRRN4CL expression — BLOOD_Leukemia

Box plot of GSG1L2 in LRRN4CL-low vs LRRN4CL-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration