LRRN4

Across TCGA patient cohorts, LRRN4 protein abundance is significantly associated with the RNA expression of many other genes, with 4,108 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible LRRN4-associated genes across cancer lineages are PLPPR2, LGALS3BP, and KCNIP3. Each is linked with LRRN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRN4-to-partner and partner-to-LRRN4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRN4 versus PLPPR2 in LUAD, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRN4→partner) and Y-score (partner→LRRN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PLPPR2 →	+0.433	+0.504	.008	.005	3	2
CCRCC	LGALS3BP →	+0.675	+1.033	<.001	<.001	3	2
CCRCC	KCNIP3 →	+1.020	+1.366	.005	<.001	3	2
LUAD	EVA1A →	+0.794	+0.716	.003	<.001	3	2
CCRCC	QSOX1 →	+0.806	+1.168	.008	.002	3	2
CCRCC	DNAJC6 →	+0.851	+0.791	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,108 associations by consensus.

LRRN4 vs PLPPR2 — LUAD

Explore this scatter interactively →