LRRIQ1

Across TCGA patient cohorts, LRRIQ1 protein abundance is significantly associated with the RNA expression of many other genes, with 104 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRRIQ1-associated genes across cancer lineages are PLLP, SLC26A8, and CA6. Each is linked with LRRIQ1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRIQ1-to-partner and partner-to-LRRIQ1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRIQ1 versus PLLP in GBM, with a Pearson correlation of 0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRIQ1→partner) and Y-score (partner→LRRIQ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLLP →	+1.600	+0.753	.007	.006	3	1
GBM	SLC26A8 →	+0.212	+0.557	.004	.005	3	1
GBM	CA6 →	+0.089	+0.557	.002	.005	3	1
GBM	SCP2D1 →	+0.419	+0.557	.002	.005	3	1
GBM	EDEM1 →	-1.076	-0.753	.008	.006	3	1
GBM	POLR3B →	-0.293	-0.540	.004	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 104 associations by consensus.

LRRIQ1 vs PLLP — GBM

Explore this scatter interactively →