LRRC8E

Across TCGA cell cohorts, LRRC8E RNA expression is significantly associated with the go_rna of many other GO terms, with 4,221 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LRRC8E-associated GO terms across cancer lineages are Wound healing, Vesicle-mediated transport to the plasma membrane, and Viral life cycle. Each is linked with LRRC8E in more than 10 cancer types. Because this analysis shows association rather than direction, both LRRC8E-to-partner and partner-to-LRRC8E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Wound healing grouped by LRRC8E-low versus LRRC8E-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC8E→partner) and Y-score (partner→LRRC8E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Wound healing →	+0.147	+1.844	<.001	<.001	3	11
OESOPHAGUS	Vesicle-mediated transport to the plasma membrane →	+0.098	+1.331	<.001	.004	3	11
STOMACH	Viral life cycle →	+0.113	+1.507	<.001	.001	3	10
STOMACH	Viral process →	+0.115	+1.598	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Membrane protein proteolysis →	+0.073	+0.544	.005	.001	3	10
OVARY	Symbiont entry into host →	+0.092	+1.261	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,221 associations by consensus.

Wound healing by LRRC8E expression — BONE

Explore this box plot interactively →