LRRC75B

Across TCGA patient cohorts, LRRC75B RNA expression is significantly associated with the protein abundance of many other proteins, with 13,921 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRRC75B-associated proteins across cancer lineages are ARHGAP4, NFIA, and IL18. Each is linked with LRRC75B in more than 5 cancer types. Because this analysis shows association rather than direction, both LRRC75B-to-partner and partner-to-LRRC75B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC75B versus ARHGAP4 in GBM, with a Pearson correlation of -0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC75B→partner) and Y-score (partner→LRRC75B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARHGAP4 →	-0.502	-0.615	<.001	<.001	3	6
BRCA	NFIA →	+0.447	+0.867	.009	.001	3	5
GBM	IL18 →	-0.708	-0.637	<.001	<.001	3	5
CCRCC	MANF →	-0.490	-0.553	<.001	.008	3	5
GBM	GRB2 →	-0.393	-0.707	<.001	<.001	3	5
CCRCC	ARVCF →	+0.419	+0.683	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,921 associations by consensus.

LRRC75B vs ARHGAP4 — GBM

Explore this scatter interactively →