LRRC75B

Across TCGA cell cohorts, LRRC75B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,486 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRRC75B-associated GO terms across cancer lineages are Sulfur amino acid metabolic process, Negative regulation of myoblast fusion, and Centromeric sister chromatid cohesion. Each is linked with LRRC75B in more than 12 cancer types. Because this analysis shows association rather than direction, both LRRC75B-to-partner and partner-to-LRRC75B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sulfur amino acid metabolic process grouped by LRRC75B-low versus LRRC75B-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC75B→partner) and Y-score (partner→LRRC75B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Sulfur amino acid metabolic process →	+0.111	+1.546	<.001	<.001	3	13
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.147	+1.151	.002	<.001	3	11
KIDNEY	Centromeric sister chromatid cohesion →	-0.143	-1.471	.001	<.001	3	10
OESOPHAGUS	Response to epidermal growth factor →	+0.116	+0.942	<.001	.001	3	10
OESOPHAGUS	Regulation of myoblast fusion →	+0.151	+0.977	<.001	<.001	3	10
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.141	+1.151	.003	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,486 associations by consensus.

Sulfur amino acid metabolic process by LRRC75B expression — KIDNEY

Explore this box plot interactively →