LRRC75A

Across TCGA pan-cancer cohorts, LRRC75A mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated LRRC75A data layer compared with 27 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher LRRC75A mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated LRRC75A expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

LUAD, LSCC, and GBM are the cancer types where LRRC75A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.847	0.949	.016	13	view →
LSCC	OS	Quartile	II,III,IV	0.448	0.746	.045	2	view →
GBM	DFS	Quartile	All	0.895	0.697	.024	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

LRRC75A–LUAD (DFS)

Open the LUAD breakdown →