LRRC74A

Across TCGA patient cohorts, LRRC74A RNA expression is significantly associated with the protein abundance of many other proteins, with 11,262 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LRRC74A-associated proteins across cancer lineages are VASH1_S313, ARHGEF6_S640, and AKR1B1. Each is linked with LRRC74A in more than 3 cancer types. Because this analysis shows association rather than direction, both LRRC74A-to-partner and partner-to-LRRC74A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC74A versus VASH1_S313 in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC74A→partner) and Y-score (partner→LRRC74A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	VASH1_S313 →	+0.473	+0.270	<.001	<.001	3	4
LSCC	ARHGEF6_S640 →	+0.745	+0.245	.001	.003	3	4
HNSC	AKR1B1 →	+0.396	+0.350	<.001	.008	3	4
GBM	ARRB1 →	+0.398	+0.543	.001	.002	3	4
HNSC	ARRB1_S412 →	+0.667	+0.749	<.001	.001	3	4
GBM	SEPTIN4 →	+0.532	+0.434	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,262 associations by consensus.

LRRC74A vs VASH1_S313 — LSCC

Explore this scatter interactively →