LRRC74A

Across TCGA cell cohorts, LRRC74A RNA expression is significantly associated with the go_rna of many other GO terms, with 103 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRRC74A-associated GO terms across cancer lineages are Regulation of T cell migration, Positive regulation of dendritic cell chemotaxis, and CENP-A containing chromatin assembly. Each is linked with LRRC74A in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC74A-to-partner and partner-to-LRRC74A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of T cell migration grouped by LRRC74A-low versus LRRC74A-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC74A→partner) and Y-score (partner→LRRC74A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of T cell migration →	+0.121	+0.009	<.001	.004	3	2
BLOOD_Leukemia	Positive regulation of dendritic cell chemotaxis →	+0.136	+0.013	.007	.008	3	2
BLOOD_Leukemia	CENP-A containing chromatin assembly →	-0.103	-0.008	<.001	.007	3	2
BLOOD_Leukemia	Equilibrioception →	+0.522	+0.009	.005	.006	3	2
BLOOD_Leukemia	Exocytosis →	+0.058	+0.016	<.001	.008	3	2
LUNG_SCLC	Retrograde trans-synaptic signaling →	+0.202	+0.061	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 103 associations by consensus.

Regulation of T cell migration by LRRC74A expression — BLOOD_Leukemia

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