Across TCGA patient cohorts, LRRC73 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,556 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRRC73-associated proteins across cancer lineages are ARFIP2, WASF2, and WIPF1. Each is linked with LRRC73 in more than 4 cancer types. Because this analysis shows association rather than direction, both LRRC73-to-partner and partner-to-LRRC73 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC73→partner) and Y-score (partner→LRRC73) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ARFIP2 →	+0.377	+0.504	<.001	<.001	3	5
OV	WASF2 →	-0.313	-0.749	<.001	<.001	3	4
BRCA	WIPF1 →	-0.475	-0.970	<.001	<.001	3	4
UCEC	IFT22 →	+0.446	+0.923	<.001	<.001	3	4
OV	LIMK1 →	-0.260	-0.486	<.001	.002	3	4
COAD	PDP1 →	-0.255	-0.350	.006	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,556 associations by consensus.

Exploration

LRRC73 survival (RNA) · tumor vs normal (RNA) · all LRRC73 data types