Across TCGA patient cohorts, LRRC73 protein abundance is significantly associated with the RNA expression of many other genes, with 3,225 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRRC73-associated genes across cancer lineages are SNRPD3, PRODH, and SEZ6L. Each is linked with LRRC73 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC73-to-partner and partner-to-LRRC73 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC73→partner) and Y-score (partner→LRRC73) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD3 →	+0.458	+0.671	<.001	.004	3	1
GBM	PRODH →	+1.031	+0.744	<.001	<.001	3	1
GBM	SEZ6L →	+2.134	+0.788	<.001	<.001	3	1
GBM	SOX10 →	+1.708	+0.710	<.001	.001	3	1
GBM	SEPTIN3 →	+0.893	+0.930	<.001	<.001	3	1
GBM	CYP2D6 →	+0.628	+0.733	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,225 associations by consensus.

Exploration

LRRC73 survival (RNA) · tumor vs normal (RNA) · all LRRC73 data types