LRRC71

Across TCGA cell cohorts, LRRC71 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,766 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible LRRC71-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Calcium-independent cell-matrix adhesion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with LRRC71 in more than 8 cancer types. Because this analysis shows association rather than direction, both LRRC71-to-partner and partner-to-LRRC71 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by LRRC71-low versus LRRC71-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC71→partner) and Y-score (partner→LRRC71) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.146	+0.423	.003	.005	3	9
LUNG_NSCLC_LUAD	Calcium-independent cell-matrix adhesion →	+0.100	+0.100	<.001	<.001	3	9
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.141	+0.423	.004	.005	3	8
OESOPHAGUS	Regulation of myoblast fusion →	+0.124	+0.423	.005	.005	3	7
SKIN	Negative regulation of calcium ion export across plasma membrane →	+0.061	+0.381	.001	.005	3	7
BREAST	Cytokinesis →	+0.056	+0.055	<.001	.007	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,766 associations by consensus.

Negative regulation of myoblast fusion by LRRC71 expression — OESOPHAGUS

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