LRRC71

Across TCGA pan-cancer cohorts, LRRC71 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of LRRC71’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LRRC71 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LRRC71 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

KIRC, LUAD, and LUSC are the cancer types where LRRC71 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LRRC71 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.205	<.001	11	view →
LUAD	Female	All	−1.611	<.001	9	view →
LUSC	Female	II,III,IV	−1.934	<.001	8	view →
KICH	All	III,IV	−0.087	.001	8	view →
THCA	Female	All	−0.091	<.001	3	view →
LIHC	All	All	+0.034	<.001	3	view →
BLCA	All	IV	−0.109	<.001	2	view →
KIRP	Male	All	−0.090	.006	2	view →
CHOL	All	All	+0.171	.011	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

LRRC71–KIRC

Open the KIRC breakdown →