LRRC71

Across TCGA cell cohorts, LRRC71 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRRC71-associated genes across cancer lineages are TSHB, NPFFR1, and CALHM4. Each is linked with LRRC71 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC71-to-partner and partner-to-LRRC71 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSHB grouped by LRRC71-low versus LRRC71-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC71→partner) and Y-score (partner→LRRC71) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TSHB →	+0.096	+3.691	.007	.002	3	1
BLOOD_Leukemia	NPFFR1 →	+0.014	+4.359	<.001	<.001	3	1
BLOOD_Leukemia	CALHM4 →	+0.019	+3.684	<.001	.004	3	1
BLOOD_Leukemia	KSR2 →	+0.468	+3.798	<.001	.004	3	1
BLOOD_Leukemia	IQCF1 →	+0.094	+4.091	<.001	.002	3	1
BLOOD_Leukemia	C2orf73 →	+0.047	+3.450	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

TSHB by LRRC71 expression — BLOOD_Leukemia

Explore this box plot interactively →