LRRC70

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LRRC70 mutation is significantly associated with the RNA expression of many other genes, with 3,723 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LRRC70-associated genes across cancer lineages are RNA5SP414, RNA5SP422, and RNA5SP416. Each is linked with LRRC70 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC70-to-partner and partner-to-LRRC70 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC70→partner) and Y-score (partner→LRRC70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP414 →+0.419+2.177<.001<.00132
BRCARNA5SP422 →+0.449+8.055<.001.00732
BRCARNA5SP416 →+1.006+8.471<.001.00532
BRCARNA5SP423 →+0.260+7.731<.001.00932
UCECRNA5SP411 →+0.755+1.765.001.00132
UCECTXN2 →+0.294+2.609.003<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,723 associations by consensus.

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