Across TCGA pan-cancer cohorts, LRRC70 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated LRRC70 data layer compared with 1 for mutation status.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher LRRC70 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LRRC70 expression acts as an unfavorable survival marker, although some lineages such as KIRC and THCA show a favorable association.

KIRP, KIRC, and THCA are the cancer types where LRRC70 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	All	0.512	0.832	<.001	112	view →
KIRC	OS	Median	All	0.856	0.753	<.001	105	view →
THCA	DFS	Median	All	0.882	0.775	<.001	44	view →
SCLC	DFS	Median	II,III,IV	0.164	0.459	.004	43	view →
LIHC	OS	Quartile	All	0.733	0.447	.003	40	view →
UCS	DFS	Tertile	IV	0.975	0.401	.024	30	view →
STAD	DFS	Tertile	All	0.500	0.647	.008	21	view →
BRCA	DFS	Quartile	III,IV	0.902	0.722	.003	20	view →
HNSC	DFS	Quartile	III,IV	0.482	0.168	.016	16	view →
THYM	DFS	Tertile	All	1.000	0.601	.007	14	view →
SKCM	OS	Tertile	III,IV	0.922	0.679	.004	13	view →
LUAD	OS	Quartile	All	0.640	0.307	.009	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

Exploration

Same gene, other analysis: LRRC70 tumor-vs-normal RNA expression · all LRRC70 data types