Across TCGA cell cohorts, LRRC70 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,905 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRRC70-associated GO terms across cancer lineages are Negative regulation of RNA export from nucleus, Positive regulation of cell proliferation involved in heart morphogenesis, and Negative regulation of tissue remodeling. Each is linked with LRRC70 in more than 5 cancer types. Because this analysis shows association rather than direction, both LRRC70-to-partner and partner-to-LRRC70 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC70→partner) and Y-score (partner→LRRC70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of RNA export from nucleus →	+0.132	+0.255	.007	.007	3	6
LARGE_INTESTINE	Positive regulation of cell proliferation involved in heart morphogenesis →	+0.099	+0.224	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Negative regulation of tissue remodeling →	-0.160	-0.180	<.001	<.001	3	5
CNS	UDP-galactose transmembrane transport →	+0.085	+0.220	<.001	<.001	3	5
SOFT_TISSUE	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.081	+0.211	.001	.008	3	5
SOFT_TISSUE	Regulation of termination of RNA polymerase II transcription →	+0.099	+0.263	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,905 associations by consensus.

Exploration

LRRC70 survival (RNA) · tumor vs normal (RNA) · all LRRC70 data types